Django Project, a powerful and clean Python Web Framework, is going to relase 1.2 as  the next milestone at the beginning of March.
For the meanwhile, you can grab the Beta2:

As part of the Django 1.2 release process, tonight we’ve released Django 1.2 beta 1, a preview/testing package that gives a little taste of some of the new features coming in Django 1.2. As with all alpha and beta packages, this is not for production use, but if you’d like to try out some of the new goodies coming in 1.2, or if you’d like to pitch in and help us fix bugs before the final 1.2 release (due in April), feel free to grab a copy and give it a spin.

Looking at the release notes we get

• Object-level permissions
• Permissions for anonymous users

Development sprints for Django 1.2 will also be taking place at PyCon US 2010, on the dedicated sprint days (February 22 through 25).

If you can, it will worth to look at.

At Gioorgi.com we have used plenty of web frameworks.

Giovanni Giorgi used Seaside,  a lot of PHP frameworks, Java Struts, RubyOnRails, and Python Django.

We have started to look for Web2Py, a compact,  easy to learn  python web framework.

From the most notable feature, it runs also on Google App Engine.
Written by an Italian University professor for teaching web development, spots a very clean design, and a robust security infrastructure.
We  suggest it because installation (and upgrading) is a snap.

Let’s take a look to it…

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We read and report:

Tonight, to clear up some problems with the packaging of the Django
1.0.1 release from Friday, we’ve released Django 1.0.2; once again,
this is a bugfix-only release, and is a recommended upgrade for anyone
targeting or using Django 1.0 or Django 1.0.1.

Weblog entry announcing the release is here:
http://www.djangoproject.com/weblog/2008/nov/18/102/
Release notes are here: http://docs.djangoproject.com/en/dev/releases/1.0.2/