Inversion of Control (IoC) is a very good idea.

But as the clever Joel Spolsky  noted, sometimes you need to be a super-natural hero to use it:

… I try not to be judgemental (HAHA!), but I think that people who use IoC containers are (A) very smart and (B) lacking in empathy for people who aren't as smart as they are. Everything makes perfect sense to them, so they have trouble understanding that many ordinary programmers will find the concepts confusing. It's the curse of knowledge. The people who understand IoC containers have trouble believing that there are people who don't understand it. …

I have trouble using Spring in at least two projects. On the third, it was a disaster, because a single software-architect-guy keeps passing around the Spring context factory as method parameter, getting beans from it!
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In the past week I learned Flask, a very young and promising  python framework. I have already learned Django, Cherrypy, Web2Py and TurboGears.

Anyway, if you are planning a medium sized project, I like to suggest you Flask, because of these feature:

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